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附件
I
實驗中動物安樂死時機及準則
Appendix I Criteria for Euthanasia of Animals Used in
Research & Teaching
國立屏東科技大學（
NPUST
）動物實驗申請表附件（
Animal Use Protocol Appendix
）
- 2012
年
7
月制訂版
背景
Background
實驗中動物安樂死時機及準則由
IACUC
制訂，主要在規範尚未完成實驗之動物
發生實驗所引起或非預期症狀，而必須將動物安樂死之狀況。
These
criteria
have
been
established
by
the
Institutional
Animal
Care
and
Use
Committee, which recognizes that euthanasia is sometimes necessary prior to the
scheduled end of a study, either because of unanticipated complications, or because of
the protocol itself.
準則
Criteria
此準則適用於所有實驗中或未實驗之動物。除了
IACUC
已審查同意之情形（如：
實驗引起之預期中症狀且能使動物痛苦程度減至最低），否則只要符合下列任一
項情況即需將動物安樂死。
These criteria apply to all animals on experimental protocols, whether manipulated or
not. Fulfillment of one criterion can constitute grounds for euthanasia. Exceptions are
permitted only if approved by the Committee as part of the protocol review process
(i.e. the clinical
signs
listed below are expected as part of the experiment and
appropriate measures are taken to minimize pain or discomfort in the animals).
1.
體重減輕
Weight loss:
體重減輕達
20-25
％，或是動物出現惡病質或消耗性症候時。
*
非生長期動物體重減輕可依據動物剛進動物房之體重或平均年齡體重為依
據。
生長期之動物體重或許不會下降，但若無法正常增重，仍應判為體重減輕。
Weight loss of 20-25% (depending on attitude, weight recorded at time of arrival,
and age: growing animals may not lose weight, but may not gain normally) or if
not measured, characterized by cachexia and wasting syndrome.
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